Name: Poison
Start: 2026-10-04T02:30:00.000Z
End: 2026-10-04T02:30:00.000Z
Location: de Maat Studio Theatre - Chicago

Chicago

<div class="ewa-rteLine">If gay’s a choice, pick your poison.</div>
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<div class="ewa-rteLine">Inside the laboratory of mad scientist Dr. Gift, a batch of mysterious potions sends his ensemble of test subjects spiraling into nightmares, fantasies, and queer comedy meltdowns. What vial will they test next? You decide.</div>
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<div class="ewa-rteLine">Poison is a 60-minute choose-your-own-adventure comedy show with no intermission.</div>
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de Maat Studio Theatre - Chicago

These non-Second City productions are original works created and produced by guest performers and ensembles. With limited runs, these performances allow for complete creative freedom and may feature artists of any experience level.

Guest Performance

A sketch is a short, scripted comedy scene. Think Key and Peele or SNL. Some people might call it a "skit," but we never do. Chicago is the home of modern sketch comedy, and today, you can experience it at all Second City locations.

Sketch Comedy

Poison

<p>The Second City&#8217;s 114th Mainstage Revue Pandemonium, Please Hold is a loud, fast, and gloriously unhinged night of comedic mayhem. The Second City’s six-person cast cranks the amps and stage dives headfirst into the chaos with blistering sketch comedy, unpredictable improv, explosive live music, and absolutely zero chill. Cathartic and wildly funny, brace for pandemonium and join us for a night of full-volume hilarity. Come scream into the abyss with us.</p>
<p><strong>Group of 16 or more? We’ll make it easy: <a href="https://www.secondcity.com/group-events" target="_blank" rel="noopener">Contact Us for Group Events</a></strong></p>


Pandemonium, Please Hold

<p><em>Reality Detox: The Improv Experience</em> is a high-energy night of improvisation from The Second City, with a few sketch surprises mixed in along the way. Built fresh each night and shaped by the people in the room, every performance is different from the last. Funny, fast, and wildly unpredictable, it&#8217;s a chance to escape reality and enjoy a night of laughter. Come be part of the comedy magic.</p>
<p><strong><a href="https://www.secondcity.com/cast-and-crew-etc-2">Meet the Cast &amp; Crew</a></strong></p>
<p><strong>Group of 16 or more? We’ll make it easy: <a href="https://www.secondcity.com/group-events" target="_blank" rel="noopener">Contact Us for Group Events</a></strong></p>


Reality Detox: The Improv Experience

<p>Chicago’s top comedians battle it out for laughs, glory, and sweet sweet points in an interactive game show, featuring a live studio audience (that’s you!) Performers go head to head in a series of hilarious challenges inspired by classic game shows like The Dating Game and The Price is Right, and current hits like Game Changer and Taskmaster. Wheel of Improv will leave your head spinning &#8211; with laughter!</p>
<p><a href="https://linktr.ee/wheelofimprov" target="_blank" rel="noopener">Check out our Linktree</a></p>


Wheel of Improv

<p><span style="color: #191919;">Find out for yourself why The Second City has been the first name in laughter for over sixty years! From the stages that launched the careers of Tina Fey, Stephen Colbert, Steve Carell and more comes the next generation of comedy superstars.</span></p>
<p><span style="color: #191919;">The Best of The Second City features some of the best sketch comedy and songs from our comedy vaults updated for the modern era, as well as some of our newest classics and our trademark improvisation performed by The Second City Touring Company’s best and brightest…and funniest!</span></p>
<p><strong>Group of 16 or more? We’ll make it easy: <a href="https://www.secondcity.com/group-events" target="_blank" rel="noopener">Contact Us for Group Events</a></strong></p>


Best of The Second City

<p>A comedic retelling of America’s greatest and most embarrassing moments.</p>


History of America part 251

<p>The perfect way to wind down after a long weekend of partying, running errands, or family time. Cheers to the Weekend brings together the finest performers around for a true variety experience. Expect a little bit of everything: stand up comedy, musical theatre, sketch, comedy burlesque, and good old fashioned improv. Audience participation is highly encouraged! Just grab your tickets, bring a few friends, and join us for one last hurrah before Monday hits.</p>


Cheers To The Weekend: A Comedy Variety Show

<p>The Stand-Up Show is a classic night of stand-up comedy focused on sharp jokes, strong voices, and big laughs. No themes, no gimmicks—just great comics doing what they do best.</p>


The Stand-up Show

<p>Low Key Lit is a new comedy show at the world famous Second City, which will feature improv and stand up comedy acts each week. You can expect some of the biggest names in comedy, locally and nationally, to perform in this amazing show. This is more than a comedy show, it is an experience. An experience, you don&#8217;t want to miss.</p>


Lowkey Lit

<p>Starship Edsel is an improvised farce set aboard Stafleet&#8217;s worst vessel, the USS Edsel. Plagued with mechanical problems and design flaws, and filled with Starfleet&#8217;s most problematic personnel, the Edsel was assigned to remain in parking orbit above a vacation planet, ordered to give VIP&#8217;s tours of an &#8220;authentic Federation Starship.&#8221; After an incursion by the Romulan Empire, the Edsel was thrust into the center of a galactic crisis. Starship Edsel follows the ship and her crew on their subsequent misadventures around the galaxy.</p>


Starship Edsel: An Improvised Star Trek Satire

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Poison

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Tickets starting at $25